Ultrafast and absolute quantification of SARS-CoV-2 on food using hydrogel RT-LAMP without pre-lysisArticle Published on 2023-01-152022-11-16 Journal: Journal of hazardous materials [Category] SARS, 치료기술, [키워드] Absolute quantification acute respiratory syndrome amplification cold chain Cold chain food contact infection coronavirus faster Food industry hydrogel Hydrogel RT-LAMP isothermal amplification microbe offer POCT point-of-care quantification reproducibility reverse transcription RNA RNA extraction RT-LAMP SARS-CoV-2 sensitivity specificity stability Surveillance Ultrafast detection. virus [DOI] 10.1016/j.jhazmat.2022.130050 PMC 바로가기
Weakly supervised segmentation of COVID-19 infection with local lesion coherence on CT imagesResearch article Published on 2023-01-012022-10-05 Journal: Biomedical Signal Processing and Control [Category] 진단, 치료기술, [키워드] absence Accuracy Algorithm approach Attention automated chain Characteristics Clinical diagnosis Complete complex Computed tomography COVID-19 COVID-19 infection CT scan dataset deep learning diagnostic edge effective expression gold standard help IMPROVE individual information labeling labor-intensive lesion Local Local Coherence Lung infection module Novel coronavirus offer overcome public health reaction Region RT-PCR scale seeking Segmentation severity the disease time-consuming Weakly Supervised [DOI] 10.1016/j.bspc.2022.104099 [Article Type] Research article
Ultraminiature optical fiber-tip directly-printed plasmonic biosensors for label-free biodetectionArticle Published on 2022-12-152022-11-15 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, [키워드] Additive Additive printing antibody AuNP Biomarker Concentration coronavirus disease detect Diagnosis diagnostics disease Diseases DNA sequence fiber gold Gold nanoparticle Gold nanoparticles imperative in vivo miniaturization offer optical Optical fiber optical fiber sensors pandemic Plasmonic biosensor point-of-care Precision Precision photoreduction. provide public health crisis SARS-CoV-2 [DOI] 10.1016/j.bios.2022.114761 PMC 바로가기
A novel statistical method predicts mutability of the genomic segments of the SARS-CoV-2 virusResearch Article Published on 2022-12-132022-10-29 Journal: Qrb Discovery [Category] COVID-19, [키워드] affected antiviral drugs approach candidate coding regions codon conserved correlated correlation determine develop disease distribution effective epitope Frequency genomic identify immunogenic peptide large-scale analysis mutability offer overcome pandemic pathogenesis of SARS-CoV-2 predict predicted Protein SARS-CoV-2 SARS-CoV-2 virus SARS-CoV2 scientist sequence Seven spike glycoprotein statistical statistical analysis target the SARS-CoV-2 virus treatments for COVID-19 Vaccine viral genome viral mutation whole genome whole genome sequence Word Ranking [DOI] 10.1017/qrd.2021.13 PMC 바로가기 [Article Type] Research Article
A hybrid random forest deep learning classifier empowered edge cloud architecture for COVID-19 and pneumonia detectionResearch article Published on 2022-12-012022-10-05 Journal: Sensors (Basel, Switzerland) [Category] 치료기술, [키워드] Accuracy Affect Algorithm Classifier cloud computing complex computation conducted COVID-19 COVID19 CT scan dataset datasets deep deep learning detect diagnose effective Efficiency evaluate False positives forest global pandemic Healthcare industry heat Heat Transfer Search algorithm identify immunization inefficient Interaction less lung CT scan methodology offer outcomes overcome Patient Pneumonia predict PROTECT random Random forest resource Support the patient virus Web services X-ray [DOI] 10.1016/j.eswa.2022.118227 [Article Type] Research article
Molecular detection of SARS-COV-2 in exhaled breath at the point-of-needArticle Published on 2022-12-012022-11-15 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] Aerosols Analysis Antigen approach approach breath contagious contagiousness detect diagnostics Direct equipment help identify impactor Infection Lab-on-a-chip less limitation molecular Nasopharyngeal swab offer Particle Pathogens patients PCR positive quantification respiratory infections RT-qPCR Saliva SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2. Spread subject temporal dynamics tested Viral load Viral RNA viral shedding Volume while [DOI] 10.1016/j.bios.2022.114663 PMC 바로가기
Adsorption of SARS-CoV-2 onto granular activated carbon (GAC) in wastewater: Implications for improvements in passive samplingArticle Published on 2022-11-152022-11-15 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 치료기술, [키워드] activated acute respiratory syndrome Adsorption Adsorption capability anticipated approaches calculated Characteristics Concentration coronavirus DI water experiment feasible granular Granular activated carbon hybrid improvement interval Laboratory limitations occurred offer Passive Passive samplers potential benefit reached reproducibility RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA sensitivity Surveillance viral pathogen virus wastewater Wastewater surveillance. [DOI] 10.1016/j.scitotenv.2022.157548 PMC 바로가기
Hotspot residues and resistance mutations in the nirmatrelvir-binding site of SARS-CoV-2 main protease: Design, identification, and correlation with globally circulating viral genomesArticle Published on 2022-11-122022-11-15 Journal: Biochemical and Biophysical Research Communication [Category] SARS, 변종, 치료제, [키워드] acute respiratory syndrome Adaptability Antiviral approved circulating coronavirus correlation COVID-19 cases COVID-19 pandemic develop drug resistance FDA highest hotspot intracellular protein Like M pro main protease Mild-to-moderate mutant Mutation mutations Nirmatrelvir offer omicron predicted Probability protease Protein design reported residue residues resistance resistance mutations robust SARS-CoV-2 SARS-CoV-2 lineage signature Signatures of adaptation. Surveillance unique variant Variation variations viral adaptation viral genome viruses [DOI] 10.1016/j.bbrc.2022.09.010 PMC 바로가기
Efficacy and safety of Treamid in the rehabilitation of patients after COVID-19 pneumonia: a phase 2, randomized, double-blind, placebo-controlled trialArticle Published on 2022-11-032022-11-16 Journal: Journal of Translational Medicine [Category] 비임상, [키워드] 1:1 Administered administration adverse event age Analysis animal model Anti-inflammatory assigned baseline Borg change changes in Chronic diseases clinical trial clinically COVID COVID pneumonia COVID-19 defined Diagnosis discharged double-blind Dyspnea Effect effective Efficacy Endpoint enrolled evaluated female female gender FEV first symptom FVC impairment increase in indicated Infection initial LLC lung damage Lung fibrosis Lung function Lungs mMRC moderate NCT04527354 offer past medical history Patient patients pharmacological treatment Placebo placebo group placebo-controlled clinical trial placebo-controlled trial Post-COVID rehabilitation predicted Prevent Primary outcome proportion pulmonary dysfunction pulmonary fibrosis Pulmonary function questionnaire Randomized Randomly reduction in Registered rehabilitation risk factor Russia SARS-CoV-2 secondary shown significant decrease significant difference stratified Support Symptoms Tolerability Treamid. Treatment Trial was done women [DOI] 10.1186/s12967-022-03660-9 PMC 바로가기
One-step colorimetric isothermal detection of COVID-19 with AI-assisted automated result analysis: A platform model for future emerging point-of-care RNA/DNA disease diagnosisResearch article Published on 2022-11-012022-10-05 Journal: Talanta [Category] SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] Accuracy Analysis analyzed approach automated Colorimetric RT-LAMP Complete Concordance COVID-19 COVID-19 testing cycle threshold Detection limit diagnosis of COVID-19 Disease diagnosis DNA downstream ENhance exhibited faster feasibility Interpretation isothermal LAMP-DETR limit machine learning majority observation offer pandemic pathogen performed Perspective platform point-of-care RT-LAMP RT-qPCR SARS-CoV-2 sensitivity specificity [DOI] 10.1016/j.talanta.2022.123375 [Article Type] Research article